ea0090ep910 | Reproductive and Developmental Endocrinology | ECE2023
Jawich Kenda
, De Toni Luca
, Al-Fahoum Sahar
, AHalabi Marwan
, Dinisio Andrea
, Santa Rocca Maria
, Ferlin Alberto
Purpose: Undercarboxylated-Osteocalcin (ucOCN), acting on its putative receptor GPRC6A, was shown to stimulate of testosterone (T) production by Leydig cells in rodents, in parallel with the hypothalamus-pituitary-gonadal axis (HPG) mediated by luteinizing hormone (LH). The aim of this cross-sectional study is to evaluate the association among serum ucOCN, rs2247911 polymorphism of GPRC6A gene and the endocrine/reproductive pattern in a cohort of infertile males, poss...